Thyroid function tests.
( Both genetic and non-genetic ( environmental ) factors seem to be operative in THYROID DISEASE ).
S.NO TSH T4 T3 INTERPRETATIONS
1 ↑ ↑ ↑ Pituitary adenoma or thyroid hormone resistance.
2 ↑N N N Sub-clinical hypothyroidism.
Reverse T3 elevated.
Wilson's ( rT3 dominance ) syndrome.
3 ↑ ↓ ↓N Hypothyroidism, Cretinism /(congenital hypothyroidism, Hoshimoto’s thyroiditis.
4 ↓ N N Mild sub-clinical. hyperthyroidism
5 ↓ ↑N ↑N Hyperthyroidism/Grave’s disease
6 ↓ ↓N ↓N Non- thyroid illness , pituatary (secondary) hypothyroidism-rare.
TSH=thyroid stimulating hormone of anterior pitutary; T4 and T3- the two hormones of thyroid gland containing
iodine;T3=Triiodothyronine;T4=Thyroxine; N=Normal;
Aspirin, Amiodarone, beta blockers, extreme illness may alter TSH results.
TSH may be decreased in the first trimester of pregnancy.
Normal range: TSH= 0.3 - 3.0 micro IU/mL ( New Criteria ); T4=4.5-12 micro g/dl;T3=60-200 ng/dl.
High fat diet increases thyrotropin ( a thyroid related hormone ) and O2 consumption.
